Free Ebook Spillover: Animal Infections and the Next Human Pandemic
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Spillover: Animal Infections and the Next Human Pandemic
Free Ebook Spillover: Animal Infections and the Next Human Pandemic
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"[Mr. Quammen] is not just among our best science writers but among our best writers, period." ―Dwight Garner, New York TimesThe next big human pandemic―the next disease cataclysm, perhaps on the scale of AIDS or the 1918 influenza―is likely to be caused by a new virus coming to humans from wildlife. Experts call such an event “spillover†and they warn us to brace ourselves. David Quammen has tracked this subject from the jungles of Central Africa, the rooftops of Bangladesh, and the caves of southern China to the laboratories where researchers work in space suits to study lethal viruses. He illuminates the dynamics of Ebola, SARS, bird flu, Lyme disease, and other emerging threats and tells the story of AIDS and its origins as it has never before been told. Spillover reads like a mystery tale, full of mayhem and clues and questions. When the Next Big One arrives, what will it look like? From which innocent host animal will it emerge? Will we be ready?
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Product details
Paperback: 592 pages
Publisher: W. W. Norton & Company; 1 edition (September 9, 2013)
Language: English
ISBN-10: 9780393346619
ISBN-13: 978-0393346619
ASIN: 0393346617
Product Dimensions:
5.5 x 1.1 x 8.3 inches
Shipping Weight: 1.1 pounds (View shipping rates and policies)
Average Customer Review:
4.7 out of 5 stars
531 customer reviews
Amazon Best Sellers Rank:
#37,423 in Books (See Top 100 in Books)
I have a weird interest in reading about diseases, and this book is one of the very best in the genre. Quammen writes for National Geographic, and he goes *everywhere.* If there was a disease outbreak in the Central African Republic in 1987, chances are, he has interviewed the doctor who first spotted the disease, the locals whose family members died, and the BSL-4 researchers in Virginia who analyzed it, and he probably also climbed down into a cave where the bat that spreads the disease roosts. This book is better than The Hot Zone. It dispels some of the over-blown language used in that book (people do not dissolve inside from Ebola.) and it is arguably just better writing.Quammen keeps the balance between travel and adventure writing on the one hand, personal interviews (of the "His desk is piled high with papers, and he's wearing blue corduroy slacks and a black turtleneck and wire-rim glasses" type), and real science writing. You learn a lot about diseases from the microscopic level to the human story of what it's like to have the disease, to the incredible courage and dedication of the people who fight the diseases, whether in the clinic or in the lab.Realistically, most of us are at essentially zero risk of dying of Ebola, but Quammen balances that with insight into things that might really harm us--SARS, AIDS, and the good old flu, which could still come roaring back as a killer.I was sorry when it ended.
Quammen makes the stories of viral discovery tangible and understandable. He manages to convey a great deal of complexity about the nature, transmission and evolution of viruses in simple and enjoyable terms. This book weaves through many narratives of mystery and intrigue - none of which have a fully complete picture yet. In a way, Quammen urges us all to keep discovering or to keep reading about those discoveries, the same way we might keep up with our favorite characters on a television show.Spillover also makes two things very clear. First, viruses can be lethal and frightening. Second, *humans* are causing this sudden tidal wave of spillover (or zoonosis) of viral infections from animal reservoirs to the human population. The book seeks not only to enlighten us to thrilling tales of discovery but also urges us to examine our role in these emerging viruses. As a part of the root cause of increased spillover, what can we, as humans, do to prevent it?
The jargon of diseases can be boring, tedious. There are a lot of acronyms and big words. Worse, we often don't know as much as we'd like -- and usually we aren't very certain of what we do know. Telling a good story given those constraints is hard. But Spillover repeatedly provides gripping stories that still impart a good understanding of what we know about zoonotic (animal-origin) diseases. Even better, the author ties disparate stories together to describe some general trend and possible causes for seemingly new infectious diseases. But I don't want to summarize the conclusions: I want you to go read it. You won't be bored and you'll learn a lot (most definitely even if you've read books like The Hot Zone or the Coming Plague).Some other notes:* The author has a less human-centric attitude and a lot of sympathy for the animals, like horses or apes, who sometimes are actually the first animal a disease spills over into only to later infect humans.* He has a wry tone. When noting the euthanasia of a large number of monkeys (even ones likely not infected with a disease), he notes no humans were euthanized despite equal exposure.* He provides full references. Some of those papers are quite readable by a non-expert such as this review ([...]) of the importance of bats as reservoirs for infectious diseases.* The stories are often told from the perspective of the scientists trying to figure out what the heck is really going on. The author is also not afraid to explain when scientists just don't know -- and how they might figure it out more.* The author went on several field collections where he might have been exposed to a disease being investigated.If I had any criticisms I would have two:* The author notes the problem of calling African hunted wild meat "bush meat" which has unsavory connotations to many Europeans and Americans despite Europeans and Americans also hunting wild animals for food. And then he still calls it that repeatedly for the rest of the book (hunted animals are a major source for new infections). I realize this makes it easier to read but it was a bit jarring.* There is a long, imagined story in the chapters on the origin HIV that is, essentially, imagined entirely with details about a possible river fisherman who gets infected with HIV early on and brings it downstream to the (then) Belgian capitol of the Congo. Elsewhere in the book when the explanation for the origin of a disease required some imagination to fill in a plausible sequence of events, the imaginary stories were a lot less elaborate. I don't think the story detracts from the accuracy of the book: something like that had to have happened to explain the origin of HIV (specifically HIV-1). I was also perfectly entertained and learned a bit about the cultures in the region, but it stood out. It might annoy some so I note you can safely skip ahead when you hit it.I call these two things out, but even so the book is still excellent. I have some interesting papers I want to read. I also feel I know more about how infectious diseases "work". Best of all, I am less fearful of them as well.
Gripping, fascinating science written in a flowing, easily digested style. To say I enjoyed this book would be an understatement. I was utterly enthralled by this book. You'll find the familiar subjects here; Ebola, HIV, etc. But you'll also find viruses you've likely never heard of, learn how biological reservoirs work (as much as they are understood at least), and the vital role of amplifiers in the lives of certain viruses. The various viruses are almost characters in and of themselves as the author delves into how, and why, they do what they do. Even the largely speculative chapter on how HIV might have gotten out of rural Africa and into the cities is fascinating.If you loved The Hot Zone, this is that book's bigger, brainier sibling. If you are at all interested in biology and physical science, you MUST read this book.
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